Understanding Estrogens
Estrogen is
actually a class of hormones with three
different subgroups: estrone, estriol and
estradiol. This group of sex hormones is
produced primarily by the ovaries in
premenopausal women. Following menopause,
estrogens are produced to some extent by the
adrenal glands and by certain fat cells. More
recently, synthetic forms of both estrogen and
progesterone (examples are Premarin, PremPro,
Progestin) have come into use.
Estrone, also known as E1, is
naturally produced by the ovaries, the
adrenal glands and in body fat. It becomes
quite prolific in the time just before
natural menopause (also called
perimenopause) and is the predominant
circulating hormone after menopause.
It is the precursor
hormone to estriol. Estrone, along with
estradiol, is known to promote cell
proliferation especially in hormone sensitive
tissue, i.e. the breast and the uterus.
Estrone's role is very similar to that of
Estradiol, but its effects are considered to be
weaker.
Estradiol, also
known as E2, is produced mainly by the ovaries
in premenopausal women. It the most predominant
of the hormones throughout a woman's life and
is considered to be the strongest of the three.
Estradiol is often the hormone of choice in
conventional Hormone Replacement
Therapy, as it is most effective for
relief of hot flashes and other severe
menopause systems. Because of its potency it is
suspected to be the cause of certain types of
cancer. Unopposed estradiol is commonly linked
to breast cancer.
Estriol, also
known as E3, is the most dominant form of
estrogen during pregnancy. In contrast to
Estradiol and Estrone, it is considered to be a
protective hormone . It does not appear to
promote cancer, and some researchers now
believe that it possesses anti-cancer activity.
For women with a history of breast cancer,
estriol may prove to be of great benefit. Due
to its protective properties, it is often
employed in natural HRT
programs.
When properly balanced
with progesterone,
estrogens (as a group) provide
significant and beneficial health
benefits.
Some of these
benefits:
- Protects against bone loss
- Reduces or eliminates hot flashes,
night sweats
- Enhances sleep quality
- Enhances mental clarity
- Enhances weight control and
management
- Believed to reduce the risk of
Alzheimers disease
- Believed to reduce the incidence of
cardiovascular disease
- Improves overall mood, sexuality and
sex drive
-
Much as an automobile requires a
quality fuel, the female body requires
an optimum mixture of hormones. When
there is an imbalance, illness and
dysfunction may begin to occur.
-
Years may go by before such
imbalances, and the resulting health
consequences, are fully realized. It is
important to know our bodies AND
communicate openly and honestly with
our trusted healthcare
practitioner!
Ok, now that we know the good
effects estrogen has on our bodies,
let's look at the negative effects when
there is too much.
Some symptoms of estrogen excess,
also known as estrogen
dominance:
- Adrenal fatigue/exhaustion
- Fibrocystic breasts
- Hair Loss
- Breast tenderness
- Weight gain,
typically fat gain around the abdomen,
hips and thighs
- Brain fog, memory and concentration
difficulties
- Loss of sex drive
- Fibromyalgia
- Thyroid dysfunction
- Insomnia
- General fatigue
- Depression
- Anxiety and/or irritability
- Inability to conceive
- Irregular and/or difficult periods
- Severe PMS symptoms,water retention,
bloating
Other serious health issues are also thought
to be linked to excess estrogen:
-
Breast Cancer, Ovarian Cancer,
Uterine Cancer, Infertility,
Autoimmune disorders, such as Lupus
and Fibromyalgia,
Gallbladder disease, Endometriosis,
Colon dysfunction and digestive
problems.
Disclaimer:
This information is not intended to diagnose,
treat or cure any disease or other medical
condition. This information is provided for
educational and informational purposes only.
Please consult with your doctor should you have
specific health questions or concerns.
Disclaimer:
This information is not intended to diagnose,
treat or cure any disease or other medical
condition. This information is provided for
educational and informational purposes only.
Please consult with your doctor should you have
specific health questions or concerns.
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